Live Attenuated PPR Vaccine

Introduction

An Indian R&D organization offers technology of live attenuated Peste des Petits ruminants (PPR) vaccine.

PPR is an acute, highly contagious and fatal rinderpest-like disease of small ruminants, and in unprotected animals the mortality may reach 60-70%. The PPR virus was first reported in India in 1987, during an outbreak in Tamil Nadu, and since then, the disease was reported from all over the country. The use of the rinderpest vaccine to protect small ruminants against PPR is contraindicated because its use induces antibodies to rinderpest, which compromises sero-surveillance for rinderpest. Hence, the present vaccine was developed for the control of PPR in sheep and goats. It is used for prophylatic vaccination against PPR in sheep and goats.

Area of Application

Pharmaceutical industry; and Veterinary medicine.

Advantages

The freeze-dried vaccine should be stored and transported at 2-8oC. The vaccine diluent should be tored in a cool and dark place. The chilled diluent (4oC) should be used for reconstituting the vaccine. For administering the dose, transfer a small aliquot of diluent from the 50 ml bottle provided (phosphate buffered saline) to the vial containing the freezedried vaccine, and mix well to ensure uniform suspension.

Then, transfer the suspension to the corresponding diluent vial and mix well. Once mixed, 1 ml of the reconstituted vaccine is injected into one sheep or goat subcutaneously. Only sterile syringes and needles should be used.

Transfer Forms

Know-how; Manufacturing licence; and Training.

For further information please contact

Asian and Pacific Centre for Transfer of Technology,
APCTT Building,
C-2 Qutab Institutional Area,
P.O.Box - 4575
New Delhi - 110 016
India