A Serum-based Kit for the Diagnosis of Visceral Leishmaniasis (Kala Azar) and PKDL

Technology Description

Visceral leishmaniasis (VL) or kala-azar is a parasitic disease, which causes death if not treated. Post-kala-azar dermal leishmaniasis (PKDL) is a skin disease and a sequel of kala-azar. Approximately 10% of the total VL cases emerge as PKDL in the Indian subcontinent and East Africa.

This technology, Dipstick, is an easy to perform, cost effective and globally validated device for the diagnosis of VL and PKDL from serum samples. The dipstick contains two lines, a control line and a test line. When colour develops on both the lines the test is positive and negative if only the control line gets colour. Results can be visualised with the naked eye without any sophisticated instrument. The device is already evaluated on many Indian, Nepalese and Brazilian patients, and Indian PKDL. Currently a multi-centre evaluation of the device is being carried out in different VL endemic regions worldwide like Sri Lanka, Nepal, India, Brazil, Iran and Sudan.

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