US Patent Granted to Indian Scientists for Work on Analgesics

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Description and Advantages

Two Indian scientists have been granted a patent by the United States Patent and Trademark Office for an invention that relates to topically applied pharmaceutical compositions for providing analgesic and anti-inflammatory relief in humans.

The patent has been granted, recently for their new medicinal invention for an analgesic anti-inflammatory composition and method of preparing the biologically active organic compound from a plant species using a dermatological acceptable carrier (code no. AK-CUR-95).

The scientists are C. Janakiram, Deputy Director (Technical), Department of Chemicals & Petrochemicals, Ministry of Chemicals & Fertilizers, New Delhi, and Dr. Md. Khalliullah, Professor, Department of Chemistry, Jawaharlal Nehru Technological University, Hyderabad, India. The patent was filed in 1999.

The Product exhibited significant thereapeutic activity in mammalian subjects. The compositions of the invention act rapidly, often provviding relief (i.e., 80 to 90 per cent reduction in pain) within 10 to 15 minutes of application, in addition to being effective for up to 24 hours with no observed side effects. Other Patents in Canada and International (PCT) are being field; PCT-Patent Cooperative Treaty is an international agreement between 104 member countries including virtually all of the major economic powers, which allow the inventors to preserve the right to file in those countries through a single application.

Janakiram had started his career with the Indian Drugs and Pharmaceuticals Ltd., Hyderabad, in 1966, which he left after 17 years to join the Union government in 1983 and is presently working as Deputy Director (Technical) in the Department of Chemicals and Petrochemicals.

Dr. Khalilullah began his career, as a lecturer with Jawaharlal Nehru Technological University, Hyderabad in 1976, became reader in 1991 and professor in 1999. He has eight scientific journals published in international journals.

The two scientists were classmates in Osmania University during 1971-73 and had to make all the efforts on their own without any financial assistance. They had to spend all their savings and also had to borrow from their friends and relatives, it is learnt.

Area Of Application

The primary object of the invention is to provide a topical analgesic and anti-inflammatory composition containing the invented compound. The compositions have patent analgesic and anti-inflammatory properties and are thus useful in the treatment of conditions involving pain and/or inflammation, such as migraines, musculoskeletal and joint disorders, low back pain, spondylosis, cramps, sprain and the like. Another object of the invention is to provide tropical therapeutic composition which can be prepared in the form of a gel, lotion, ointment, spray, liquid, liniment, and the like.


Pharmabiz, August 2, 2001