Enzymatic Synthesis of Glyco-Conjugates

Introduction

Glyco - conjugates are molecules in which sugars are linked to amines, alkyl and protein molecules. Many of these are biologically important as cell surface receptors, as molecules involved in cell - cell recognition, cell - drug recognition processes. Enzymatic synthesis of these special molecules provides alternative routes to conventional medicine. We have shown applications of a new recombinant E. coli expressed b-glucosidase in the synthesis of these of these molecules. Many novel oligosaccharides, alkyl glucosides of commercial importance have been synthesised using this enzyme under laboratory conditions.

Special Features:

Special compounds (carbohydrates) can be synthesised using this enzyme.

Prospective Users:

Pharmaceutical industry.

Keywords:

Alkyl-glucosides, oligosaccharide synthesis

Type of Technology:

Process, Products.

Glossary:

Glyco conjugates:molecules in which sugars are linked with amine alkyl or protein group

For further information please contact :

The Director
Foundation for Innovation and Technology Transfer
Indian Institute of Technology Delhi
Hauz Khas, New Delhi-110016
Tel : 91-011-26597167, 26857762, 26581013
Fax : 91-011-26851169
E-mail : mdfitt@gmail.com