Bio-Synthesis, Production and Formulation of Sophorolipids for the Purpose of Sanitizing/ Sterilizing Fruits and Vegetables

Introduction

The technology is aimed at converting a chiral alpha-hydroxy ketone to chiral amino alcohol by using a transaminase, using an amine donor Isopropyl amine, which in turn is converted to acetone. The alpha hydroxy ketone R-PAC is a chiral intermediate coming from yeast whole cell biotransformation. The transaminase is expressed in E.coli and the transamination is also a whole cell biotransformation .

State of Development

Early Stage Validation

Unique Features of the Product/Technology

The technology features a possibility to replace an existing commercial totally synthetic chemistry process, with a Green transaminase based whole cell E.Coli biotransformation

Market Potential

Current production of the product through synthetic route is about 70 TPA. Although increase in HIV cases is not seen, there is a stable market for Efavirenz and therefore Norephedrine. Norephedrine derivatives are also intermediates to make amphetamines .

For further information please contact :  

Biotechnology Industry Research Assistance Council (BIRAC)
1st Floor ,MTNL Building ,9 ,
CGO Complex, Lodhi Road,
New Delhi-110003
E-mail: birac.dbt@nic.in
Phone: + 91-11-24389600